Lightyear — Step 1 Coverage Audit
The Lightyear Step 1 deck covers 648 of 901 subtopics in our USMLE Step 1 content outline — a 71.9% coverage rate. Is the Lightyear deck enough for Step 1? No. With 253 subtopics receiving zero cards and 43 more receiving only 1–3 cards, Lightyear leaves gaps across every organ system that will show up on exam day. It is a strong primary deck, but not a standalone resource.
Lightyear is a video-based Anki deck built to follow Boards & Beyond lectures. Its 14,073 cards are structured to reinforce concepts as you watch, making it ideal for students who prefer a lecture-first workflow over pure Anki grinding. The deck's strongest domains are Biochemistry (94.5% coverage, 2,807 cards), Public Health Sciences (90.0%), and General Pathology (88.9%) — areas where Lightyear outperforms most competing decks. The weaknesses are significant: Microbiology covers only 17 of 60 subtopics (28.3%), General Pharmacology hits just 20 of 36 (55.6%), and Musculoskeletal/Skin lands at 61.1%. High-yield gaps include Hemodynamic Profiles of Shock, Antihypertensives Overview, and ACS Antiplatelet and Anticoagulant Therapy — all zero-card subtopics with guaranteed Step 1 representation.
This page presents the only independent coverage audit of the Lightyear deck mapped against all 901 canonical USMLE Step 1 subtopics. The data below shows where Lightyear is strong, where it is thin, and what you need to supplement before test day.
Step 1 cards = cards that mapped to our 901-subtopic Step 1 content outline. Cards covering other material are excluded.
Coverage by area
| Area | Coverage | Cards |
|---|---|---|
| Biochemistry | 52/55 (94.5%) | 2,807 |
| Public Health Sciences | 27/30 (90.0%) | 573 |
| General Pathology | 24/27 (88.9%) | 1,139 |
| Immunology | 28/33 (84.8%) | 2,561 |
| Gastrointestinal | 62/74 (83.8%) | 3,705 |
| Hematology and Oncology | 51/61 (83.6%) | 2,351 |
| Renal | 46/57 (80.7%) | 2,352 |
| Neurology and Special Senses | 47/59 (79.7%) | 2,673 |
| Cardiovascular | 48/64 (75.0%) | 2,337 |
| Respiratory | 48/65 (73.8%) | 2,321 |
| Reproductive | 52/80 (65.0%) | 2,555 |
| Endocrine | 34/53 (64.2%) | 3,240 |
| Psychiatry | 48/75 (64.0%) | 1,573 |
| Musculoskeletal, Skin, and Connective Tissue | 44/72 (61.1%) | 2,448 |
| General Pharmacology | 20/36 (55.6%) | 542 |
| Microbiology | 17/60 (28.3%) | 187 |
| Total | 648/901 (71.9%) | 13,931 mapped |
Gaps — zero cards (253 subtopics)
High-yield gaps
- HYFermentation and NAD+ RegenerationBiochemistry
- HYHemodynamic Profiles of ShockCardiovascular
- HYRight Ventricular InfarctionCardiovascular
- HYACS Antiplatelet and Anticoagulant TherapyCardiovascular
- HYAdrenergic Receptors and AgonistsCardiovascular
- HYAntihypertensives OverviewCardiovascular
- HYAntiplatelets and AnticoagulantsCardiovascular
- HYVasopressors and InotropesCardiovascular
- HYOsteoporosisEndocrine
- HYCarcinoid Tumor and Carcinoid SyndromeEndocrine
- HYInsulin Preparations (Rapid, Short, Intermediate, Long)Endocrine
- HYSulfonylureas and MeglitinidesEndocrine
- HYMetforminEndocrine
- HYGLP-1 Agonists and DPP-4 InhibitorsEndocrine
- HYSGLT2 InhibitorsEndocrine
- HYThyroid Pharmacotherapy (Levothyroxine, Methimazole, PTU, Iodine)Endocrine
- HYOsteoporosis PharmacotherapyEndocrine
- HYAcetaminophen Toxicity and NACGeneral Pharmacology
- HYSedative and Opioid ReversalGeneral Pharmacology
- HYAnticoagulant ReversalGeneral Pharmacology
- HYAntidote Quick Table (High-Yield)General Pharmacology
- HYTransfusion ReactionsHematology and Oncology
- HYAlkylating AgentsHematology and Oncology
- HYAntimetabolitesHematology and Oncology
- HYAntitumor AntibioticsHematology and Oncology
- HYTargeted Biologics and Checkpoint InhibitorsHematology and Oncology
- HYMHC Class I and IIImmunology
- HYVaccine Types and ContraindicationsImmunology
- HYBacterial Staining and StructureMicrobiology
- HYEncapsulated OrganismsMicrobiology
- HYBacterial ExotoxinsMicrobiology
- HYEndotoxin (LPS) and Septic ShockMicrobiology
- HYStreptococcus pneumoniaeMicrobiology
- HYStreptococcus pyogenes (Group A Strep)Microbiology
- HYStreptococcus agalactiae (Group B Strep)Microbiology
- HYOther Streptococci and EnterococciMicrobiology
- HYListeria monocytogenesMicrobiology
- HYEscherichia coli PathotypesMicrobiology
- HYEnteric Gram-Negative RodsMicrobiology
- HYPseudomonas aeruginosaMicrobiology
- HYHelicobacter pyloriMicrobiology
- HYGram-Negative Respiratory PathogensMicrobiology
- HYLyme Disease (Borrelia burgdorferi)Microbiology
- HYMycobacterium tuberculosisMicrobiology
- HYMycoplasma pneumoniaeMicrobiology
- HYAspergillusMicrobiology
- HYCryptococcus neoformansMicrobiology
- HYDimorphic Systemic MycosesMicrobiology
- HYPneumocystis jiroveciiMicrobiology
- HYBlood/Tissue Protozoa (Malaria, Babesia, Trypanosoma, Leishmania)Microbiology
- HYViral Structure, Genome, and Replication (Survey)Microbiology
- HYHuman PapillomavirusMicrobiology
- HYHepatitis B VirusMicrobiology
- HYParamyxoviruses (Measles, Mumps, RSV, Parainfluenza)Microbiology
- HYHIV Virology and Opportunistic InfectionsMicrobiology
- HYNucleic Acid Synthesis InhibitorsMicrobiology
- HYAntifungalsMicrobiology
- HYSeptic ArthritisMusculoskeletal, Skin, and Connective Tissue
- HYNSAIDs and AcetaminophenMusculoskeletal, Skin, and Connective Tissue
- HYCorticosteroids (Systemic and Topical)Musculoskeletal, Skin, and Connective Tissue
- HYDMARDs and BiologicsMusculoskeletal, Skin, and Connective Tissue
- HYOsteoporosis PharmacologyMusculoskeletal, Skin, and Connective Tissue
- HYAntiepileptic Drugs (AEDs)Neurology and Special Senses
- HYParkinson Disease PharmacotherapyNeurology and Special Senses
- HYPost-Traumatic Stress Disorder (PTSD)Psychiatry
- HYOpioid Use — Intoxication, Withdrawal, MaintenancePsychiatry
- HYSuicide Risk Assessment and Risk FactorsPsychiatry
- HYSelective Serotonin Reuptake Inhibitors (SSRIs)Psychiatry
- HYTricyclic Antidepressants (TCAs)Psychiatry
- HYAtypical Antidepressants (Bupropion, Mirtazapine, Trazodone)Psychiatry
- HYLithiumPsychiatry
- HYValproate as Mood StabilizerPsychiatry
- HYAtypical (Second-Generation) AntipsychoticsPsychiatry
- HYBenzodiazepinesPsychiatry
- HYIncidence, Prevalence, and MortalityPublic Health Sciences
- HYRenin-Angiotensin-Aldosterone SystemRenal
- HYPotassium Handling and RegulationRenal
- HYCalcium and Phosphate Handling (PTH / Vitamin D)Renal
- HYLoop DiureticsRenal
- HYThiazide DiureticsRenal
- HYACE Inhibitors and ARBs — Renal EffectsRenal
- HYRh Isoimmunization and RhoGAMReproductive
- HYPostpartum Hemorrhage and EndometritisReproductive
- HYHPV (Condyloma and Cancer)Reproductive
- HYChlamydia trachomatisReproductive
- HYNeisseria gonorrhoeaeReproductive
- HYSyphilis (Primary, Secondary, Tertiary, Congenital)Reproductive
- HYCombined Oral ContraceptivesReproductive
- HYSERMs (Tamoxifen, Raloxifene)Reproductive
- HYCOPD — Acute ExacerbationRespiratory
- HYCOPD — Chronic ManagementRespiratory
- HYβ2-Agonists (SABA / LABA)Respiratory
- HYInhaled and Systemic CorticosteroidsRespiratory
Other gaps
- Hereditary Hemorrhagic Telangiectasia (Osler-Weber-Rendu)Biochemistry
- Carbohydrate Structure and DigestionBiochemistry
- Post-MI Arrhythmia and ICD IndicationsCardiovascular
- Dressler SyndromeCardiovascular
- Takotsubo (Stress) CardiomyopathyCardiovascular
- Vasospastic (Prinzmetal) AnginaCardiovascular
- Cocaine-Induced Chest Pain / MICardiovascular
- Peripheral Artery DiseaseCardiovascular
- Acute Limb IschemiaCardiovascular
- Syncope (Cardiac, Vasovagal, Orthostatic)Cardiovascular
- … and 150 more
Thin spots — 1 to 3 cards (43 subtopics)
- 1NeuroblastomaEndocrine
- 1Paralytic IleusGastrointestinal
- 1Proton Pump InhibitorsGastrointestinal
- 1Heavy Metal Poisoning and ChelatorsGeneral Pharmacology
- 1Anemia of Chronic DiseaseHematology and Oncology
- 1Aplastic AnemiaHematology and Oncology
- 1Myelodysplastic SyndromeHematology and Oncology
- 1HIV ImmunologyImmunology
- 1Compartment SyndromeMusculoskeletal, Skin, and Connective Tissue
- 1Typical (First-Generation) AntipsychoticsPsychiatry
- … and 33 more
How to pair Lightyear with other resources
Lightyear is built as a companion to Boards & Beyond, and that pairing is where it performs best. B&B lectures directly address many of the conceptual gaps Lightyear's cards leave behind — particularly in Cardiovascular pharmacology, where the deck has zero cards on Antihypertensives Overview, Vasopressors and Inotropes, and Antiplatelets and Anticoagulants. Treat B&B video content as primary and use Lightyear cards for active recall on top of those lectures, not as a substitute for them. For Microbiology — the deck's weakest area at just 28.3% coverage (17/60 subtopics) — supplement with a dedicated microbiology resource or add Anki cards from Sketchy Micro to fill the 43 uncovered subtopics.
First Aid is a high-value supplement for flagging Lightyear's thin spots. Cross-referencing First Aid chapters against the gap list above — especially in Psychiatry (64.0% coverage), Endocrine (64.2%), and General Pharmacology (55.6%) — identifies which First Aid pages need active card creation or targeted reading. Building even a small set of custom cards for the 253 zero-coverage subtopics, prioritizing high-yield gaps like Carcinoid Syndrome (Endocrine) and Fermentation/NAD+ Regeneration, closes the most dangerous blind spots across the full exam blueprint.
Frequently asked questions
Is Lightyear enough for Step 1?
Lightyear covers 648 of 901 subtopics in our USMLE Step 1 content outline (71.9%), which makes it a strong primary deck but not a standalone resource. It has 253 subtopics with zero cards, including high-yield areas like Antihypertensives Overview and Hemodynamic Profiles of Shock. Pair it with Boards & Beyond videos and targeted First Aid review to close the gaps.
How many cards are in Lightyear?
The Lightyear Anki deck contains 14,073 total cards, with 13,931 mapped to USMLE Step 1 subtopics. The deck is structured to follow Boards & Beyond lectures, with cards organized by B&B video topic for a lecture-first active recall workflow.
What does Lightyear not cover for Step 1?
Lightyear's biggest gap is Microbiology, which covers only 17 of 60 Step 1 subtopics (28.3%) with just 187 cards. General Pharmacology (55.6%) and Musculoskeletal/Skin (61.1%) are also significantly underrepresented. Specific zero-card gaps include Antihypertensives Overview, ACS Antiplatelet and Anticoagulant Therapy, Vasopressors and Inotropes, and Osteoporosis.
What is the weakest subject in the Lightyear Anki deck for Step 1?
Microbiology is Lightyear's weakest subject by a wide margin, covering only 17 of 60 Step 1 subtopics (28.3%) with 187 cards — leaving 43 subtopics completely uncovered. General Pharmacology (20/36 subtopics, 55.6%) and Psychiatry (48/75 subtopics, 64.0%) are the next weakest areas. Supplement Microbiology with Sketchy Micro or a dedicated deck before your exam.